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54th ERA-EDTA Congress

 

3rd-6th June 2017 Madrid
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Discussion forum - 54th ERA-EDTA Congress
    Topic - Renal transplantation - Epidemiology & outcome II

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Poster: 812
Visits: 8
Title: ASSOCIATION OF FETUIN GENE POLYMORPHISMS WITH CORONARY ARTERY CALCIFICATIONS AND MORTALITY IN RENAL TRANSPLANT AND CHRONIC KIDNEY DISEASE PATIENTS
Authors: Svetlana Jovicic Pavlovic , Sanja Simic Ogrizovic2,3, Violeta Dopsaj4, Ivana Novakovic5, Zoran Bukumiric6, Radomir Naumovic1,3,
Centre: Clinic for Nephrology, Clinical Centre of Serbia, Belgrade

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ASSOCIATION OF FETUIN GENE POLYMORPHISMS WITH CORONARY ARTERY CALCIFICATIONS AND MORTALITY IN RENAL TRANSPLANT AND CHRONIC KIDNEY DISEASE PATIENTS

Svetlana Jovicic Pavlovic
Thread initiator
Subspeciality
Reg: 5/21/2017 10:10:00 PM

Comment# 1

Pre-existing vascular calcifications in CKD are independent predictor of CV and all cause mortality following transplantation. Some patients remain free of VC, so we can assume that such patients may be genetically protected or have high levels of calcification inhibitors, or both. Serum fetuin A is important circulating inhibitor of vascular calcifications. Detection of patients with genetic predisposition for lower fetuin levels may be important for early prevention.

Comment added on 5/21/2017 10:10:00 PM 
     
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